Tricylic antidepressants are a class of antidepressants that affect certain neurotransmitters in the nervous system resulting in changes in mood and other physical symptoms. Tricyclic antidepressants are prescribed to treat a variety of physical disorders, including depression, anxiety and pain.
Tricyclic antidepressants are sometimes used as a treatment for IBS due to their beneficial effects on symptoms.
For more in-depth discussions of tricylic antidepressants as a treatment for IBS, see:

