Is Cascara Sagrada Safe?
Safety information on cascara sagrada is a bit sobering. The Food and Drug Administration (FDA) issued a ruling in 2002 that banned the inclusion of cascara sagrada in over-the-counter products due to safety concerns. Regular use of cascara sagrada has been linked with an increased risk of hepatitis and colorectal cancer.Safety Recommendations
Cascara sagrada is not recommended for use by pregnant women or children under the age of 12. If you suffer from any type of health problem, it is essential that you get clearance from your doctor before taking cascara sagrada due to potential adverse reactions. Cascara sagrada should not be taken for more than seven days in a row.The Bottom Line
People often assume that all herbal supplements are safe. Cascara sagrada is a good example of the fact that caution needs to be applied before initiating any form of treatment, even one that is sold over-the-counter. In my opinion, it would be well worth your time to explore alternative treatments for constipation.
For more laxative options:
Sources:
Food and Drug Administration Status of Certain Additional Over-the-Counter Drug Category II and III Active IngredientsNadir, A., Reddy, D. & Van Thiel, D. “ Cascara sagrada-induced intrahepatic cholestasis causing portal hypertension: case report and review of herbal hepatotoxicity” The American Journal of Gastroenterology 2000 95: 3634–3637.
Siegers, C., Hertzberg-Lottin, E., Otte, M. & Schneider, B. “Anthranoid laxative abuse--a risk for colorectal cancer?” Gut 1993 34:1099-1011.
