Amitriptyline for IBS in Adolescents
In this study, 33 children, ages 12 to 18, who were recently diagnosed with IBS were split into two treatment groups. One group received amitriptyline and the other group received a placebo. Several symptom questionnaires were administered at the beginning of the study and again at various intervals for a total of 13 weeks. At the study’s end, the teens who received amitriptyline experienced significant improvement in quality of life. Improvements were also seen in terms of a reduction of diarrhea and abdominal pain.
For more information on prescription medication options for IBS:
- Prescription Medication for Diarrhea Predominant Irritable Bowel Syndrome
- Prescription Medication for Constipation Predominant Irritable Bowel Syndrome
Bahar, R., Collins, B., Steinmetz, B. & Ament, M. “Double-blind Placebo-Controlled Trial of Amitriptyline for the Treatment of Irritable Bowel Syndrome in Adolescents” The Journal of Pediatrics 2008 152:685-689.


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